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Correspondence
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Volume 339:1639-1640 November 26, 1998 Number 22
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Enoxaparin in Neurosurgical Patients

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 by Weitz, J. I.
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 by Agnelli, G.
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To the Editor: The study by Agnelli et al. (July 9 issue)1 of the efficacy of enoxaparin (a low-molecular-weight heparin) plus graded compression stockings as prophylaxis against deep-vein thrombosis in neurosurgical patients is both sound and timely. Unfortunately, their conclusion that this combination "should be the method of choice for prophylaxis against venous thromboembolism in the majority of patients undergoing elective neurosurgery" may be premature. Such a statement would require this combination to be superior to all alternatives with respect to efficacy, safety, and cost. Although Agnelli et al. showed that the combination of enoxaparin and compression stockings is as . . . [Full Text of this Article]

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