Edited by John M. Coffin, Stephen H. Hughes, and Harold E. Varmus. 843 pp. Plainview, N.Y., Cold Spring Harbor Laboratory Press, 1997. $180. ISBN 0-87969-497-1.
Retrovirology is a mature yet rapidly evolving field, and thisexcellent book provides a very complete approach, integratingall the scientific aspects of the topic except epidemiology.Retrovirology started with the discovery at the turn of thecentury of tumor-associated viruses in chickens and continuedwith the identification of other tumor-associated viruses ina variety of animals, including mammals. At the beginning ofthe 1960s, progress in the study of cultured cells revealedthat, although retroviruses have an RNA genome, they have replicationand transformation properties that set them apart from othersingle-stranded RNA viruses, such as poliovirus. At that . . . [Full Text of this Article]
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