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Previous Volume 339:1710-1714 December 3, 1998 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Olivieri et al. (Aug. 13 issue)¹ retrospectively evaluated liver-biopsy specimens from patients with thalassemia who were treated with deferiprone and concluded that progression of fibrosis in 5 of 14 patients was due to the drug. The authors minimized the potential role of known factors that could, on their own, explain the progression of fibrosis in the five patients and the fact that many had received inadequate chelation therapy before they started taking deferiprone. Fibrosis and even cirrhosis are prominent in patients with thalassemia, as illustrated by the fact that 3 of 18 patients had cirrhosis before treatment . . . [Full Text of this Article]

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