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Volume 339:1864 December 17, 1998 Number 25
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Autoimmune Aspects of Lung Disease

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Edited by D.A. Isenberg and S.G. Spiro. 276 pp., illustrated. Boston, Birkhäuser Verlag, 1998. Swiss Fr. 238. ISBN 3-7643-5719-3.

It is hard to imagine that just a short time ago it was possible to think about lung disease with little attention to immunity and inflammation. After all, pulmonary pathophysiology was, and remains, best described in biomechanical and biochemical terms. Asthma is a disease of the airways, with impaired air movement that results in increased expiratory pressures and lung volumes and disastrous air trapping. Occupational lung diseases often result in diffuse scarring that leads to decreased lung volumes. Tumors are space-occupying lesions of the lung airway or parenchyma. In pneumonia, air exchange is impaired even as the febrile patient's metabolic . . . [Full Text of this Article]




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