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Previous Volume 339:245-253 July 23, 1998 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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When bleeding is the consequence of a specific defect of hemostasis, the goal of treatment is to correct the defect. A typical example is the replacement of factor VIII by transfusion in patients with hemophilia. Specific treatment may be impossible, however, because bleeding may result from multiple defects or because no cause can be identified. In such situations, nontransfusional drugs that help to stop bleeding are indicated.¹ These drugs may also be indicated for patients who refuse blood transfusion or for those who undergo surgical procedures associated with large blood losses necessitating many transfusions of donated blood. Many nontransfusional hemostatic . . . [Full Text of this Article]

Antifibrinolytic Amino Acids

Primary Menorrhagia

Gastrointestinal Bleeding

Bleeding in the Urinary Tract

Oral Bleeding in Congenital and Acquired Coagulation Disorders

Bleeding in Patients with Thrombocytopenia

Bleeding after Thrombolytic Treatment

Reducing Blood Loss during Cardiac Surgery

Joint Replacement

Orthotopic Liver Transplantation

Side Effects

Aprotinin

Cardiac Surgery

Orthotopic Liver Transplantation

Side Effects

Desmopressin

Congenital Bleeding Disorders

Acquired Bleeding Disorders

Cirrhosis

Reducing Blood Loss during Surgery

Side Effects

Hemostatic Drugs as Prophylaxis in Patients Undergoing Cardiac Surgery

Conjugated Estrogens

Conclusions

Source Information

From the Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Istituto di Ricovero e Cura a Carattere Scientifico Maggiore Hospital, and the University of Milan, Milan, Italy.

Address reprint requests to Dr. Mannucci at Via Pace 9, 20122 Milan, Italy.

References

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