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Correspondence
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Volume 339:269-270 July 23, 1998 Number 4
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Hemochromatosis Presenting as Acute Liver Failure after Iron Supplementation

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To the Editor: Hemochromatosis is an autosomal recessive disorder of iron overload caused by a mutation of the HFE gene on the short arm of chromosome 6. The principal clinical features are diabetes mellitus, cirrhosis, hypogonadism, and cardiac failure,1,2 and the age at clinical presentation is usually 40 years or older.1 We report a case of acute liver failure after iron supplementation in the setting of unrecognized hemochromatosis.

A 29-year-old woman was admitted to the hospital because of a two-day history of jaundice, asthenia, hypercholuria, and hypocholia. The patient had been well until two months before admission, when she began . . . [Full Text of this Article]

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