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Correspondence
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Volume 339:405-406 August 6, 1998 Number 6
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Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

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 by Palella, F. J.
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To the Editor: Palella et al. (March 26 issue)1 reported that the use of more intensive antiretroviral therapies is responsible for declines in both morbidity and mortality in patients with AIDS. We conducted a study to evaluate the impact of protease inhibitors on the rates of selected opportunistic processes and mortality and found similar results.

Our study population came from a public human immunodeficiency virus (HIV) outpatient clinic in New Orleans. All subjects and data were from the Adult Spectrum of Disease study, a prospective study funded by the Centers for Disease Control and Prevention examining the natural history of . . . [Full Text of this Article]

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