A low serum potassium concentration is perhaps the most commonelectrolyte abnormality encountered in clinical practice. Whendefined as a value of less than 3.6 mmol of potassium per liter,hypokalemia is found in over 20 percent of hospitalized patients.1The majority of these patients have serum potassium concentrationsbetween 3.0 and 3.5 mmol per liter, but as many as one quarterhave values below 3.0 mmol per liter. Comparable data are notavailable for outpatients, but a low serum potassium concentrationhas been found in 10 to 40 percent of patients treated withthiazide diuretics.2 Hypokalemia is usually well . . . [Full Text of this Article]
Normal Regulation of Potassium Balance
Clinical Spectrum
Drug-Induced Causes Due to Transcellular Shifts
2-Sympathomimetic Drugs
Xanthines
Other Drugs
Drug-Induced Causes Due to Abnormal Losses of Potassium
Diuretics
Drugs with Mineralocorticoid or Glucocorticoid Effects
Other Drugs
Laxatives and Enemas
Nondrug Causes Due to Transcellular Shifts
Nondrug Causes Due to Inadequate Dietary Intake
Nondrug Causes Due to Abnormal Losses of Potassium
Losses in Stool
Loss through the Kidney
Metabolic Alkalosis
Metabolic Acidosis
Other Disorders
Principles of Potassium Replacement
Source Information
From the Department of Medicine, University of Vermont College of Medicine, Burlington.
Address reprint requests to Dr. Gennari at Burgess 315, Fletcher Allen Health Care, Burlington, VT 05401.
References
Related Letters:
Treatment of Hypokalemia
Agarwal A., Wingo C. S., Robertson J. I. S., Gennari F. J.
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N Engl J Med 1999;
340:154-155, Jan 14, 1999.
Correspondence
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