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Previous Volume 339:520-532 August 20, 1998 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Micrococcus, which, when limited in its extent and activity, causes acute suppurative inflammation (phlegmon), produces, when more extensive and intense in its action on the human system, the most virulent forms of septicæmia and pyæmia.¹

In an elegant series of clinical observations and laboratory studies published in 1880 and 1882, Ogston described staphylococcal disease and its role in sepsis and abscess formation.^1,2 More than 100 years later, Staphylococcus aureus remains a versatile and dangerous pathogen in humans. The frequencies of both community-acquired and hospital-acquired staphylococcal infections have increased steadily, with little change in overall mortality. Treatment of these infections has . . . [Full Text of this Article]

Staphylococcal Components and Products

Genome

Cell Wall

Capsule

Surface Proteins

Toxins

Enzymes and Other Bacterial Components

Genetic Regulation of Virulence-Determinant Expression

Epidemiology of Staphylococcal Disease

Colonization and Infection

Transmission

Temporal Trends in S. aureus Disease

Pathogenesis of Staphylococcal Disease

Invasive Infections

Toxin-Mediated Disease

Host Response to Infection

Diseases Caused by S. aureus

Bacteremia

Endocarditis

Metastatic Infections

Sepsis

Toxic Shock Syndrome

Mechanisms of Resistance to Antimicrobial Agents

Treatment of S. aureus Infection

Prevention of Staphylococcal Disease

Source Information

From the Division of Infectious Diseases, Department of Medicine, Montefiore Medical Center, and the Departments of Medicine, Microbiology, and Immunology, Albert Einstein College of Medicine — both in Bronx, N.Y.

Address reprint requests to Dr. Lowy at the Department of Medicine, Montefiore Medical Center, 111 E. 210th St., Bronx, NY 10467.

References

Related Letters:

Staphylococcus aureus Infections
Blot S., Vandewoude K., Colardyn F., Conde A., Tacconelli E., Tumbarello M., Cauda R., Lowy F. D.
Extract | Full Text  
N Engl J Med 1998; 339:2025-2027, Dec 31, 1998. Correspondence

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