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Previous Volume 339:599-603 August 27, 1998 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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During childhood and young adulthood, the skeleton accrues virtually all the bone mineral it will ever have.¹ Since the aging process is associated with bone loss, the more bone mass one gains in the formative years, the less likely it is that increased bone resorption and decreased bone formation will result in osteoporosis. Hence, the failure to achieve optimal peak bone mass is a pathogenetic mechanism in osteoporosis. The sex steroids are critically important in helping to establish peak bone mass for both sexes. Girls with estrogen deficiency do not achieve optimal peak bone mass.^2,3,4 Similarly, achievement of peak bone . . . [Full Text of this Article]

Case Report

Methods

Biochemical Determinations

Bone Densitometry

Results

Discussion

Source Information

From the Departments of Medicine (J.P.B.), Pharmacology (J.P.B.), and Pediatrics (A.M., J.B.), College of Physicians and Surgeons, Columbia University, New York; and the Department of Pediatrics, University of California, San Francisco (M.M.G.). Presented in abstract form at the 19th Annual Meeting of the American Society for Bone and Mineral Research, Cincinnati, September 10–14, 1997 (J Bone Miner Res 1997;12:Suppl:S678).

Address reprint requests to Dr. Bilezikian at the Department of Medicine, College of Physicians and Surgeons, 630 W. 168th St., New York, NY 10032.

References

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