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Figure 1. A 31-year-old woman was receiving gonadotropin stimulation as part of an in vitro fertilization protocol. By day 10 of her menstrual cycle a 5-cm ovarian cyst had developed. The cyst was aspirated transvaginally under sonographic guidance. Cytospin preparations of the specimen were stained with Papanicolaou stain. A single oocyte, approximately 150 µm in diameter, with coarsely granular cytoplasm (yolk) and a barely visible nucleus, was identified (Panel A, x60). The oocyte had a visible zona pellucida, and a layer of granulosa (i.e., follicular) cells surrounded the oocyte, forming the corona radiata. The granulosa cells had undergone . . . [Full Text of this Article] |
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