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Correspondence
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Volume 339:632-634 August 27, 1998 Number 9
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Expression of Renin in Glomerular Nonjuxtaglomerular Cells in a Child with a Hypertensive Bartter's-Like Syndrome

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To the Editor: Bartter's-like syndromes are characterized by hypokalemia, hypochloremia, metabolic alkalosis, and normal blood pressure despite hyperreninemia and hyperaldosteronism.1 We report on an infant with a Bartter's-like syndrome characterized by hypertension, hypercalcemia, and the ectopic expression of renin in glomerular nonjuxtaglomerular and adrenal vascular smooth-muscle cells.

The patient was a girl who was delivered at 30 weeks' gestation by cesarean section because of fetal tachycardia. The infant's maternal great-grandmother and maternal great-aunt had hypertension. She weighed 1620 g. The neonatal course was characterized by hyponatremia, hypochloremia, hypophosphatemia, metabolic acidosis, hypercalcemia, hypomagnesemia, and anemia. The blood urea nitrogen and serum . . . [Full Text of this Article]

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