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Previous Volume 339:634-635 August 27, 1998 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The letter by Steinmuller (April 23 issue)¹ reports the problems, including hemolysis, that occurred when sterile water was used to dilute 25 percent albumin. The problems occur because although the albumin is concentrated about fivefold in 25 percent albumin, the electrolytes are not, so that the resulting solution is close to isotonic and therefore can be safely administered intravenously. When diluted with water or dextrose in water, it becomes proportionally low in electrolytes.

Although the response by the representatives of the Food and Drug Administration (FDA)² is correct with regard to the recommendation that dilution with 5 . . . [Full Text of this Article]

References

Related Letters:

A Dangerous Error in the Dilution of 25 Percent Albumin
Steinmuller D. R., Pierce L. R., Gaines A., Varricchio F., Epstein J. S.
Extract | Full Text  
N Engl J Med 1998; 338:1226-1227, Apr 23, 1998. Correspondence

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