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Previous Volume 339:636 August 27, 1998 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100% of the full text and any section headings.

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To the Editor: In the discussion of Case 15-1998 (May 14 issue),¹ Canavan's disease is said to be characterized by "the absence of N-acetylaspartic acid activity on magnetic resonance spectroscopy." In actuality, N-acetylaspartic acid is elevated in Canavan's disease.^2,3

Jonathan Breslau, M.D.
Radiological Associates of Sacramento
Sacramento, CA 95814

References

1. Case Records of the Massachusetts General Hospital (Case 15-1998). N Engl J Med 1998;338:1448-1456. [Free Full Text]
2. Grodd W, Krageloh-Mann I, Klose U, Sauter R. Metabolic and destructive brain disorders in children: findings with localized proton MR spectroscopy. Radiology 1991;181:173-181. [Free Full Text]
3. Marks HG, Caro PA, Wang ZY, et al. Use of computed tomography, magnetic resonance imaging, and localized 1H magnetic resonance spectroscopy in Canavan's disease: a case report. Ann Neurol 1991;30:106-110. [CrossRef][Medline]

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