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Review Article
Drug Therapy
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Volume 340:780-788 March 11, 1999 Number 10
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Treatment of Attention-Deficit–Hyperactivity Disorder
Josephine Elia, M.D., Paul J. Ambrosini, M.D., and Judith L. Rapoport, M.D.

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Attention-deficit–hyperactivity disorder (ADHD) is a common but controversial syndrome characterized by developmentally inappropriate hyperactivity, impulsivity, and inattention.1 The disorder, which continues throughout life,2,3,4,5,6,7 usually begins in childhood and is characterized by excessive activity, even when adjusted for developmental level, and limited behavioral control. A severely affected child, in whom behavioral control is absent, is exhausting to care for.

ADHD is controversial despite the acceptance of specific diagnostic criteria. That it is an extreme form of commonly occurring types of behavior rather than a disorder with discrete determinants is suggested by genetic studies, including a large study of twins, in which . . . [Full Text of this Article]

Prevalence

Genetics

Course

Treatment

Stimulant-Drug Preparations

Adverse Effects

Antidepressant Drugs

Alpha-Adrenergic–Agonist Drugs

Psychosocial Interventions

Other Treatments

Conclusions


Source Information

From the Department of Child and Adolescent Psychiatry, Children's Hospital of Philadelphia, and the Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia (J.E.); the Department of Psychiatry, Division of Child and Adolescent Psychiatry, MCP–Hahnemann University, Philadelphia (P.J.A.); and the Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Md. (J.L.R.).

Address reprint requests to Dr. Elia at the Children's Hospital of Philadelphia, Main Bldg., Rm. 3636, 34th St. and Civic Center Blvd., Philadelphia, PA 19104-4399.

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