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Volume 340:814-815 March 11, 1999 Number 10
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Interstitial Nephritis in a Patient Taking Creatine

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To the Editor: Creatine is being widely used as a possible performance-enhancing substance. Its safety, however, is being debated in both the scientific community1,2,3 and in the popular press. We report on a patient who had transient renal insufficiency while taking creatine.

A previously healthy 20-year-old man presented with a four-day history of nausea, vomiting, and bilateral flank pain that began approximately four weeks after he started taking 5 g of creatine (pure creatine monohydrate, ProPerformance Laboratories, Pittsburgh) orally four times a day. He had stopped the creatine and had not taken any medications or other food supplements. His blood . . . [Full Text of this Article]

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