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Previous Volume 340:858-868 March 18, 1999 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Carcinoid tumors were first described over 100 years ago by Lubarsch, who found multiple tumors in the distal ileum of two patients at autopsy.¹ The term karzinoide was used by Oberndorfer in 1907 to describe similar tumors that appeared to behave in a more indolent fashion than typical adenocarcinomas.² Carcinoid tumors have subsequently been reported in a wide range of organs but most commonly involve the lungs, bronchi, and gastrointestinal tract.

Biology

Carcinoid tumors are thought to arise from neuroendocrine cells. They are characterized histologically by positive reactions to silver stains and to markers of neuroendocrine tissue, including neuron-specific enolase, synaptophysin, . . . [Full Text of this Article]

Classification

Incidence

Pulmonary Carcinoid Tumors

Gastric Carcinoid Tumors

Carcinoid Tumors of the Small Intestine

Appendiceal Carcinoid Tumors

Carcinoid Tumors of the Colon

Rectal Carcinoid Tumors

Metastatic Carcinoid Tumors

Treatment with Somatostatin Analogues

Carcinoid Heart Disease

Management of Hepatic Metastases

Medical Management of Metastatic Disease

Source Information

From the Department of Adult Oncology, Dana–Farber Cancer Institute and Harvard Medical School, Boston.

Address reprint requests to Dr. Kulke at the Dana–Farber Cancer Institute, 44 Binney St., Boston, MA 02115.

References

Related Letters:

Carcinoid Tumors
Kema I. P., Willemse P. H.B., de Vries E. G.E., Taal B. G., Hoefnagel C., Rutgers M., Barham M., Kulke M. H., Mayer R. J.
Extract | Full Text  
N Engl J Med 1999; 341:453-455, Aug 5, 1999. Correspondence

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