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Previous Volume 340:1049-1050 April 1, 1999 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the United States, screening for open neural-tube defects is now part of routine prenatal care.¹ The two most common defects (anencephaly and open spina bifida) are important causes of perinatal morbidity and mortality. Although prenatal screening with the use of maternal serum alpha-fetoprotein measurements is widespread, there is little information available on the effect such screening has on the prevalence of these defects. Such information would be helpful for health care planning. A pilot study was sponsored by the New England Regional Genetics Group, both to document the current use of prenatal screening and to establish . . . [Full Text of this Article]

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