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Correspondence
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Volume 340:1287-1288 April 22, 1999 Number 16
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Cord-Blood Transplants

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 by Rubinstein, P.
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To the Editor: In the excellent paper by Rubinstein et al. (Nov. 26 issue)1 on cord-blood transplants, the number of nucleated cord-blood cells that were transfused per kilogram of the recipient's weight emerged as the main influence on engraftment. The serologic status of the recipient with respect to cytomegalovirus was irrelevant to engraftment and survival.

We have recently evaluated the results of 133 cord-blood transplantations listed in the Eurocord Registry up to April 1998. We found that the dose of nucleated cord-blood cells (measured before the blood was frozen) ranged from 9.7 million to 552 million per kilogram (median, 43.5 . . . [Full Text of this Article]

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