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Previous Volume 340:1418-1421 May 6, 1999 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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A 16-year-old black girl presented to the emergency room with increased thirst, frequent urination, fatigue, and an 11-kg weight loss in the preceding two to three weeks.

The triad of polydipsia, polyuria, and polyphagia with weight loss is a classic presentation of diabetes mellitus. Among adolescents, type 1 (autoimmune) diabetes mellitus is the most probable diagnosis. With these three symptoms, the differential diagnosis is quite limited, but diabetes insipidus, either nephrogenic or central, should also be considered. Diabetes insipidus is characterized by polydipsia, polyuria, and weight loss, but not polyphagia, and the weight loss is due to a decreased caloric . . . [Full Text of this Article]

Commentary

Source Information

From the Maccabi Juvenile Diabetes Center, Ramat Hasharon, Israel (O.P.-H.); and the Division of Endocrinology, Department of Pediatrics, University of Colorado Health Science Center, Denver (P.Z.).

Address reprint requests to Dr. Pinhas-Hamiel at Maccabi Juvenile Diabetes Center, 5 Usishkin St., P.O. Box 1773, Ramat Hasharon, 47117 Israel, or at c12502@coop.co.il.

References

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• Hannon, T. S., Rao, G., Arslanian, S. A. (2005). Childhood Obesity and Type 2 Diabetes Mellitus. Pediatrics 116: 473-480 [Abstract] [Full Text]  
• Libman, I. M., Pietropaolo, M., Arslanian, S. A., LaPorte, R. E., Becker, D. J. (2003). Evidence for Heterogeneous Pathogenesis of Insulin-Treated Diabetes in Black and White Children. Diabetes Care 26: 2876-2882 [Abstract] [Full Text]  
• Pinero-Pilona, A., Litonjua, P., Aviles-Santa, L., Raskin, P. (2001). Idiopathic Type 1 Diabetes in Dallas. Diabetes Care 24: 2013-2013 [Full Text]  
• Piñero-Piloña, A., Litonjua, P., Aviles-Santa, L., Raskin, P. (2001). Idiopathic Type 1 Diabetes in Dallas, Texas: A 5-year experience. Diabetes Care 24: 1014-1018 [Abstract] [Full Text]