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Previous Volume 340:1443 May 6, 1999 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Recreational use of 3,4-methylenedioxymethamphetamine (MDMA, or "ecstasy"), a hallucinogen, has increased both in Europe and the United States.¹ This substance is manufactured in illicit laboratories from a variety of organic ketone precursors. MDMA, which is structurally related both to the stimulant amphetamine and to the hallucinogen mescaline, promotes the release of both serotonin and dopamine from synaptic terminals.² We report a case of parkinsonism after repeated use of this drug.

A 29-year-old man had slight clumsiness of his upper and lower extremities in August 1998. During the following four weeks he began to have difficulty walking and . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Ricaurte, G. A., Yuan, J., Hatzidimitriou, G., Cord, B. J., McCann, U. D. (2002). Severe Dopaminergic Neurotoxicity in Primates After a Common Recreational Dose Regimen of MDMA ("Ecstasy"). Science 297: 2260-2263 [Abstract] [Full Text]  
• Kalant, H. (2001). The pharmacology and toxicology of "ecstasy" (MDMA) and related drugs. CMAJ 165: 917-928 [Abstract] [Full Text]  
• Borg, G. J., Sewell, R. A., Cozzi, N. V., Baggott, M., Mendelson, J., Jones, R., Mintzer, S., Hickenbottom, S., Gilman, S. (1999). More about Parkinsonism after Taking Ecstasy. NEJM 341: 1400-1401 [Full Text]