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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 340:1661-1669 May 27, 1999 Number 21
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Case 16-1999— A 71-Year-Old Man with Progressive Weakness and a Gammopathy
David A. Chad, and Nancy L. Harris

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Presentation of Case

A 71-year-old, right-handed man was admitted to the hospital because of progressive muscle weakness and difficulty swallowing.

The patient had been well until one year earlier, when he had several bouts of pulmonary and paranasal-sinus infections that were treated with amoxicillin. Nine months before admission, his voice was becoming progressively softer and hyponasal. Two months later, muscle weakness developed in the arms and legs, especially on the right side, and subsequently worsened, with loss of muscle bulk. Five months before admission, the patient began to have falls because of a right footdrop, and he had occasional leg cramps. Painless dysphagia . . . [Full Text of this Article]

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Dr. David A. Chad's Diagnoses

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