To the Editor: Eradication of the human immunodeficiency virus(HIV) is a difficult goal to achieve, because a reservoir ofreplication-competent HIV is established in resting CD4 T lymphocytessoon after infection and persists after years of highly activeantiretroviral treatment.1 A more realistic alternative to lifelongcumbersome, toxic, and expensive treatments is to control HIV,as occurs in patients with long-term nonprogression of the disease.
A patient, who has become known as "the Berlin patient," wastreated soon after acute HIV infection, before complete seroconversionon Western blotting, with a combination of hydroxyurea (400mg three times daily),2 didanosine . . . [Full Text of this Article]
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