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Previous Volume 340:1843-1844 June 10, 1999 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Penicillin resistance has been an increasing problem in the treatment of infections due to gram-positive cocci over the past 15 years.¹ Much of the concern has related to the rising minimal inhibitory concentrations (MICs) of antibiotics required to suppress Streptococcus pneumoniae, but sharp declines in penicillin sensitivity have also been observed in streptococci of the viridans group and S. mitis in particular.^2,3,4 I report a case of prosthetic-valve endocarditis resulting from infection with an S. mitis organism that was fully resistant to penicillin.

The patient, a 48-year-old man with a long history of intravenous drug abuse and . . . [Full Text of this Article]

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N Engl J Med 1999; 341:1239-1240, Oct 14, 1999. Correspondence

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• Sabella, C., Murphy, D., Drummond-Webb, J. (2001). Endocarditis Due to Streptococcus mitis With High-Level Resistance to Penicillin and Ceftriaxone. JAMA 285: 2195-2195 [Full Text]  
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