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Correspondence
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Volume 340:2001-2002 June 24, 1999 Number 25
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Respiratory Viruses and Acute Otitis Media

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 by Eskola, J.
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 by Heikkinen, T.
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To the Editor: Heikkinen et al. (Jan. 28 issue)1 studied the prevalence of various respiratory viruses in samples of middle-ear effusions from children with acute otitis media and found that respiratory syncytial virus had the highest rate of detection. Although respiratory viruses may differ in their capacity to invade the middle ear, any comparison of the frequencies of and differences in infection depends heavily on the sensitivity of the methods used to determine the presence of viral infection. The methods used by Heikkinen et al. were not optimal for detecting certain respiratory viruses, particularly human rhinoviruses and coronaviruses.

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