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Correspondence
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Volume 340:393-394 February 4, 1999 Number 5
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Case 23-1998: Fat Embolism

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 by Rosen, J. M.
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To the Editor: Rosen and Mark (July 23 issue)1 did not include dose-intensive chemotherapy or treatment with granulocyte colony-stimulating factor (G-CSF) among the possible causes of atraumatic fat embolism syndrome. We describe two patients with atraumatic fat embolism in whom symptoms developed suddenly and were rapidly fatal.

Patient 1 was a 59-year-old-woman with recurrent diffuse large-cell lymphoma who received a second course of therapy consisting of 60 mg of etoposide per kilogram of body weight intravenously on day 1, 3 g of cyclophosphamide per square meter of body-surface area intravenously on day 2, 200 mg of paclitaxel per square meter . . . [Full Text of this Article]

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