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Previous Volume 340:557-559 February 18, 1999 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In the United States, recombinant growth hormone is approved for use in children for three conditions: growth hormone deficiency, Turner's syndrome, and chronic renal insufficiency before transplantation. Because the supply of growth hormone is unlimited and treatment has few adverse effects, it is not surprising that there is interest in treating children with short stature who do not have classic growth hormone deficiency.

But what is short stature? Is it a height that is more than 2 SD below the mean for age and sex (less than the 3rd percentile)? If so, should treatment with growth hormone in an otherwise . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Gill, D G (2006). "Anything you can do, I can do bigger?": the ethics and equity of growth hormone for small normal children.. Arch. Dis. Child. 91: 270-272 [Abstract] [Full Text]  
• Cuttler, L. (2005). Safety and Efficacy of Growth Hormone Treatment for Idiopathic Short Stature. J. Clin. Endocrinol. Metab. 90: 5502-5504 [Full Text]  
• Cuttler, L., Silvers, J. B. (2004). Growth Hormone Treatment for Idiopathic Short Stature: Implications for Practice and Policy. Arch Pediatr Adolesc Med 158: 108-110 [Full Text]  
• Lee, P. A., Kendig, J. W., Kerrigan, J. R. (2003). Persistent Short Stature, Other Potential Outcomes, and the Effect of Growth Hormone Treatment in Children Who Are Born Small for Gestational Age. Pediatrics 112: 150-162 [Full Text]  
• Carel, J.-C., Chatelain, P., Rochiccioli, P., Chaussain, J.-L. (2003). Improvement in Adult Height after Growth Hormone Treatment in Adolescents with Short Stature Born Small for Gestational Age: Results of a Randomized Controlled Study. J. Clin. Endocrinol. Metab. 88: 1587-1593 [Abstract] [Full Text]  
• Rappold, G. A., Fukami, M., Niesler, B., Schiller, S., Zumkeller, W., Bettendorf, M., Heinrich, U., Vlachopapadoupoulou, E., Reinehr, T., Onigata, K., Ogata, T. (2002). Deletions of the Homeobox Gene SHOX (Short Stature Homeobox) Are an Important Cause of Growth Failure in Children with Short Stature. J. Clin. Endocrinol. Metab. 87: 1402-1406 [Abstract] [Full Text]  
• Finkelstein, B. S., Imperiale, T. F., Speroff, T., Marrero, U., Radcliffe, D. J., Cuttler, L. (2002). Effect of Growth Hormone Therapy on Height in Children With Idiopathic Short Stature: A Meta-analysis. Arch Pediatr Adolesc Med 156: 230-240 [Abstract] [Full Text]  
• (1999). Long-Term Benefit of Growth Hormone in Children?. JWatch Psychiatry 1999: 20-20 [Full Text]  
• (1999). Long-Term Benefit of Growth Hormone in Children with Idiopathic Short Stature. JWatch General 1999: 6-6 [Full Text]