

View larger version (253K):
[in this window]
[in a new window]
|
Figure 1. A 71-year-old woman who had had a basal-cell carcinoma presented with a six-week history of an enlarging lesion on the upper part of her right arm (Panel A). The well-circumscribed crateriform nodule, which had a keratotic core and measured 2 by 2 cm, appeared clinically to be a benign keratoacanthoma. An excisional biopsy was performed. Histologic analysis revealed a proliferation of squamous cells that were derived from the epidermis and formed a large, keratin-filled crater lined by thickened, papillary, glycogen-rich epithelium, findings consistent with a diagnosis of keratoacanthoma (Panel B; hematoxylin and eosin, x10). One year . . . [Full Text of this Article] |