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Correspondence
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Volume 340:732-735 March 4, 1999 Number 9
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Dilated Cardiomyopathy in HIV-Infected Patients

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 by Dec, G. W.
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 by Barbaro, G.
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To the Editor: In their study of dilated cardiomyopathy in patients with human immunodeficiency virus (HIV) infection, Barbaro et al. (Oct. 15 issue)1 did not ascertain whether nutritional abnormalities were present, as Lipshultz notes in his accompanying editorial.2 Causes of left ventricular dysfunction in patients with HIV infection include cardiomyopathies due to wasting and deficiencies of trace elements.2 Selenium deficiency is an independent factor associated with high mortality among HIV-infected patients.3 As a component of glutathione peroxidase, selenium is involved in the antioxidant response in cells and tissues. In patients with HIV infection, selenium deficiency may be due to the . . . [Full Text of this Article]

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