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Previous Volume 341:764-765 September 2, 1999 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Bräuninger, A. PubMed Citation

To the Editor: Bräuninger et al. (April 22 issue)¹ identified a common germinal-center B-cell precursor for both Reed–Sternberg cells and non-Hodgkin's lymphoma cells in two patients with composite lymphoma. We studied five patients who had classic composite lymphoma with features of Hodgkin's disease and non-Hodgkin's lymphoma in the same lymph node to determine whether the two neoplasms were clonally related.

One patient presented with a combination of nodular-sclerosis Hodgkin's disease and a high-grade B-cell lymphoma; the others had mixed-cellularity Hodgkin's disease and low-grade B-cell lymphoma. Single cells were isolated from formalin-fixed, paraffin-embedded sections after immunohistochemical staining for CD20, CD15, CD30, . . . [Full Text of this Article]

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