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Correspondence
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Volume 341:849-850 September 9, 1999 Number 11
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More on the Depressive Effects of Interferon Alfa

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To the Editor: In a recent letter, Capuron and Ravaud described their use of a depression rating scale as a method of predicting depressive symptoms associated with high doses of interferon alfa (April 29 issue).1 We strongly endorse the authors' recommendation of a routine psychiatric assessment before treatment with interferon alfa. However, we consider their conclusions — that "the effects of interferon alfa on mood depend on the initial affective state of the patients" and that a base-line measurement of mood symptoms constitutes "an easy way to identify patients who are at risk for mood disorders" — to be both . . . [Full Text of this Article]

References


Related Letters:

Prediction of the Depressive Effects of Interferon Alfa Therapy by the Patient's Initial Affective State
Capuron L., Ravaud A.
Extract | Full Text  
N Engl J Med 1999; 340:1370, Apr 29, 1999. Correspondence



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