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The end of the 20th century marks a pivotal point in the development of respiratory medicine. There has been an explosive growth in knowledge relevant to the field and the application of bioengineering, molecular biology, and microbiology to improve the treatment of acute and chronic disorders of the respiratory system. Some innovations, such as the discovery of the cystic fibrosis gene and progress in the field of adult respiratory distress syndrome, were so important that Fishman's Pulmonary Diseases and Disorders had to be updated between editions. This information is incorporated in the third edition, which was edited by an editorial
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