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Review Article
Current Concepts
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Volume 341:893-900 September 16, 1999 Number 12
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Fever in Immunocompromised Patients
Philip A. Pizzo, M.D.

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The past two decades have witnessed an increase in the number of patients who are immunocompromised as a consequence of a primary or secondary immunodeficiency disorder or from the use of agents that depress one or more components of the immune system. Broadly defined, an immunocompromised host has an alteration in phagocytic, cellular, or humoral immunity that increases the risk of an infectious complication or an opportunistic process such as a lymphoproliferative disorder or cancer.1 Patients may also be immunocompromised if they have an alteration or breach of their skin or mucosal defense barriers that permits microorganisms to cause either . . . [Full Text of this Article]

Fever, Immunosuppression, and Infection

Need for Urgent Evaluation and Intervention

Dominant Organisms Associated with Infection

Initial Evaluation of Fever

Management of Infectious Complications


Source Information

From the Department of Medicine, Children's Hospital, and the Department of Pediatrics, Harvard Medical School — both in Boston.

Address reprint requests to Dr. Pizzo at Children's Hospital, 300 Longwood Ave., Boston, MA 02115, or at pizzo_p@a1.tch.harvard.edu.

References


Related Letters:

Fever in Immunocompromised Patients
Serody J. S., Pizzo P. A.
Extract | Full Text  
N Engl J Med 2000; 342:217-218, Jan 20, 2000. Correspondence

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