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Previous Volume 341:901-908 September 16, 1999 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

A 68-year-old woman was admitted to the hospital because of rapidly progressive dementia and a gait disorder.

The patient had been well until about one year earlier, when she began to have vague problems with her memory. Three months before admission, a rapid progression of cognitive deficits was observed, with word-finding problems and confusion. On one occasion the patient tripped and thereafter began to experience "quivering" in the legs, with loss of coordination. She became barely able to stand, even with the aid of a walker. Over a period of weeks, a gait apraxia, worsening ataxia, lethargy, progressive hypophonia, and . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnosis

Dr. Leslie A. Shinobu's Diagnosis

Pathological Discussion

Anatomical Diagnosis

References

Related Letters:

Case 28-1999: Creutzfeldt–Jakob Disease
Zeidler M., Green A. J.E., Zerr I., Shinobu L. A.
Extract | Full Text  
N Engl J Med 2000; 342:292-293, Jan 27, 2000. Correspondence

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• Solvason, H. B., Harris, B., Zeifert, P., Flores, B. H., Hayward, C. (2002). Psychological Versus Biological Clinical Interpretation: A Patient With Prion Disease. Am. J. Psychiatry 159: 528-537 [Full Text]  
• Zeidler, M., Green, A. J.E., Zerr, I., Shinobu, L. A. (2000). Case 28-1999: Creutzfeldt-Jakob Disease. NEJM 342: 292-293 [Full Text]