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Previous Volume 341:927-928 September 16, 1999 Number 12

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Edited by Charles H. Hennekens. 472 pp., illustrated. Philadelphia, W.B. Saunders, 1999. $130. ISBN 0-7216-6867-4.

This outstanding, thoroughly comprehensible and comprehensive, well-edited book succeeds admirably in its intention to serve as a resource on clinical trials in cardiovascular disease for those in research and in clinical practice. It provides an extensive, instructive review of statistical methods, a critical review of treatment trials, and a review of trials regarding prevention — all of which explain and epitomize modern evidence-based medicine. This book is a worthy companion to Braunwald's Heart Disease, permitting readers to decide on their own the appropriateness of clinical guidelines and therapies, and is well worth the expense.

The first section explains and clarifies . . . [Full Text of this Article]

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