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Since the 1960s, screening for breast cancer by mammography has been the subject of a number of controlled trials. These studies showed that, among 45-to-64-year-old women, regular mammography was associated with a 30 percent decrease in mortality due to breast cancer. A large tumor with high-grade histologic features and lymph-node metastases are associated with a poor prognosis. Mammographic screening can detect small tumors with low-grade histologic patterns that have not spread to the lymph nodes all features of a good prognosis.
In 1987, the National Health Service Breast Screening Programme (NHSBSP) was founded in the United Kingdom with the
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