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Previous Volume 341:1121-1125 October 7, 1999 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Drowning accounts for more accidental deaths in children and adolescents than all other causes except motor vehicle accidents.^1,2,3 Many of these fatalities are attributed to lack of supervision, trauma, alcohol or drug use, or seizures. However, an appreciable number of drownings have no satisfactory explanation. In these situations, cardiac arrhythmias, particularly those associated with the long-QT syndrome, may be an important consideration. The long-QT syndrome comprises a group of genetically distinct arrhythmogenic cardiovascular disorders, each resulting from a mutation in one of five genes encoding cardiac ion channels or auxiliary ion-channel subunits: KVLQT1 (at the LQT1 locus), HERG (at LQT2), . . . [Full Text of this Article]

Case Report

Methods

Results

Novel 9-bp Deletion in KVLQT1

Screening of Family Members

Effect of Genetic Testing on Clinical Management

Discussion

Source Information

From the Department of Pediatric and Adolescent Medicine, Section of Pediatric Cardiology, Mayo Eugenio Litta Children's Hospital (M.J.A., D.J.T., C.J.P.), and the Department of Laboratory Medicine and Pathology (W.D.E.), Mayo Foundation, Rochester, Minn.

Address reprint requests to Dr. Ackerman at the Department of Pediatric and Adolescent Medicine, Mayo Eugenio Litta Children's Hospital, Mayo Foundation, Rochester, MN 55905, or at ackerman.michael@mayo.edu.

References

Related Letters:

The Long-QT Syndrome
Allan W. C., Ackerman M. J., Porter C.-b. J.
Extract | Full Text  
N Engl J Med 2000; 342:514-515, Feb 17, 2000. Correspondence

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