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Previous Volume 341:1239-1240 October 14, 1999 Number 16 Next

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To the Editor: Thrombocytopenia is a common hematologic disorder in persons infected with the human immunodeficiency virus (HIV).¹ Although often asymptomatic, the thrombocytopenia in these patients may be associated with a variety of bleeding abnormalities. Corticosteroids, intravenous immune globulin, and interferon can improve HIV-associated thrombocytopenia, although the responses are not sustained after the cessation of treatment.¹ Several studies have shown increases in platelet counts in HIV-infected patients with thrombocytopenia who were treated with zidovudine,^1,2 but these responses were not sustained. Maness et al. reported a similar effect of indinavir,³ but their report did not include data on the viral load.

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References

Related Letters:

Prosthetic-Valve Endocarditis Caused by Penicillin-Resistant Streptococcus mitis
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N Engl J Med 1999; 340:1843-1844, Jun 10, 1999. Correspondence

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