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Correspondence
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Volume 341:1241-1242 October 14, 1999 Number 16
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HHV-8 Peripheral-Blood Viral Load and the Titer of Antibodies against HHV-8

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To the Editor: In their letter to the editor, Sitas et al. (June 17 issue)1 report a relation between the titers of anti–human herpesvirus 8 (HHV-8) antibodies in mothers and the prevalence of anti–HHV-8 antibodies in their children. The authors explain this relation by suggesting that high titers of antibodies against HHV-8 indicate a large number of HHV-8–infected cells in the peripheral blood (i.e., a large viral load). Likewise, in their editorial in the same issue, Jaffe and Pellett2 suggest that the correlation between high titers of HHV-8 antibodies and an increased risk of Kaposi's sarcoma, reported by Sitas et . . . [Full Text of this Article]

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