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Previous Volume 341:1397-1399 October 28, 1999 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In their article, Wolfe et al. (June 17 issue)¹ stated that the number of deaths associated with the use of nonsteroidal antiinflammatory drugs (NSAIDs) in the United States every year is almost identical to that associated with AIDS. This statement, misinterpreted by the press, seriously overstates the risks associated with the use of NSAIDs.

Wolfe et al. extrapolated the estimated number of deaths associated with NSAIDs from death rates in the Arthritis, Rheumatism, and Aging Medical Information System (ARAMIS). Although data from ARAMIS are valuable for examining relative risks, one cannot extrapolate incidence rates from ARAMIS to . . . [Full Text of this Article]

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