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Volume 341:123-124 July 8, 1999 Number 2
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Blood Transfusions in Critical Care

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 by Hébert, P. C.
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To the Editor: In their multicenter trial of transfusion requirements in critical care, Hébert et al. (Feb. 11 issue)1 demonstrate that, in the case of red-cell transfusion, the adage "more is better" is not always true. However, their recommendation of a threshold for red-cell transfusion of a hemoglobin concentration of 7.0 g per deciliter may not be appropriate at high altitudes.

Although a hemoglobin concentration of 7.0 to 9.0 g per deciliter may suffice at an atmospheric pressure of 760 mm Hg at sea level, it yields a dangerously low partial pressure of arterial oxygen at a higher altitude (such . . . [Full Text of this Article]

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