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Previous Volume 341:1546 November 11, 1999 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Palomaki et al. (April 1 issue)¹ reported recently that 96 women from Maine had pregnancies, with estimated or actual dates of delivery between 1991 and 1996, in which open spina bifida or anencephaly developed in the fetuses. In addition, they found no decrease in the prevalence of these preventable birth defects.

In 1991, the Medical Research Council Vitamin Study Research Group reported the results of a randomized, controlled trial that found that synthetic folic acid taken in the form of a pill prevents 72 percent of cases of spina bifida and anencephaly.² Had an effective program of . . . [Full Text of this Article]

References

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