To the Editor: Chen et al. (July 22 issue)1 report an increasingprevalence of Streptococcus pneumoniae strains with reducedsusceptibility to fluoroquinolones in Canada. We have foundsimilar results in Barcelona, Spain.
Of 2822 pneumococcal isolates studied in our institution from1991 through 1998, 57 (2.0 percent) were resistant to ciprofloxacin(minimal inhibitory concentration, 4 µg per milliliter).We have seen an increase of ciprofloxacin-resistant pneumococci,from 0.9 percent (6 of 675 strains) in 19911992 to 3.0percent (22 of 727 strains) in 19971998 (P=0.004). Theuse of fluoroquinolones in Spain has also increased during thepast 13 years, from . . . [Full Text of this Article]
References
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