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Correspondence
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Volume 341:1548 November 11, 1999 Number 20
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Mother-to-Infant Transmission of the Human Immunodeficiency Virus during Primary Infection

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To the Editor: The efficacy of antiretroviral-drug therapy in preventing mother-to-infant transmission of the human immunodeficiency virus (HIV) has led to the recommendation of universal testing of pregnant women as early as possible after conception.1 However, this strategy precludes the identification of women who acquire HIV infection later in pregnancy, including women who are infected during the peripartum period. Either scenario can result in erroneous exclusion of infant HIV infection, as has been documented for congenital syphilis.2 Early identification of infants with HIV infection is important for the initiation of prophylaxis against Pneumocystis carinii pneumonia and antiretroviral-drug therapy. We report . . . [Full Text of this Article]

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