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Previous Volume 341:1688-1689 November 25, 1999 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The article by Klebanoff and colleagues¹ in this issue of the Journal adds to the growing body of literature examining the association of caffeine intake with adverse pregnancy outcomes and developmental problems. This study reports an association between spontaneous abortions, primarily in the second trimester, and unusually high levels of consumption of caffeine, equivalent to more than six cups of coffee a day.

Unlike previous studies, in which exposure was estimated from the women's reports of the amount of caffeinated beverages they consumed, Klebanoff et al. used a biologic marker of caffeine intake, the levels of the caffeine metabolite paraxanthine . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Svikis, D. S., Berger, N., Haug, N. A., Griffiths, R. R. (2005). Caffeine Dependence in Combination With a Family History of Alcoholism as a Predictor of Continued Use of Caffeine During Pregnancy. Am. J. Psychiatry 162: 2344-2351 [Abstract] [Full Text]  
• Bracken, M. B., Triche, E. W., Belanger, K., Hellenbrand, K., Leaderer, B. P. (2003). Association of Maternal Caffeine Consumption with Decrements in Fetal Growth. Am J Epidemiol 157: 456-466 [Abstract] [Full Text]  
• Biaggioni, I., Davis, S. N. (2002). Caffeine: A Cause of Insulin Resistance?. Diabetes Care 25: 399-400 [Full Text]  
• Cnattingius, S., Signorello, L. B., Anneren, G., Clausson, B., Ekbom, A., Ljunger, E., Blot, W. J., McLaughlin, J. K., Petersson, G., Rane, A., Granath, F. (2000). Caffeine Intake and the Risk of First-Trimester Spontaneous Abortion. NEJM 343: 1839-1845 [Abstract] [Full Text]  
• Griffiths, R. R., Vernotica, E. M. (2000). Is Caffeine a Flavoring Agent in Cola Soft Drinks?. Arch Fam Med 9: 727-734 [Abstract] [Full Text]  
• (2000). Coffee Drinking and the Risk for Miscarriage. Journal Watch Dermatology 2000: 20-20 [Full Text]  
• (1999). Coffee Drinking and the Risk for Miscarriage. JWatch General 1999: 5-5 [Full Text]