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Correspondence
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Volume 341:1857-1858 December 9, 1999 Number 24
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Case 23-1999: Infantile Pulmonary Tuberculosis

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 by Husson, R. N.
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To the Editor: In the July 29 Case Record,1 a 10-month-old infant with pulmonary tuberculosis was discharged while receiving antituberculous treatment that included ethambutol. The use of ethambutol in a patient of this age is fraught with danger.

Retrobulbar optic neuritis is the most serious adverse effect of ethambutol. Axial or central neuritis — the only form reported in patients taking ethambutol in daily doses of less than 30 mg per kilogram of body weight — involves the papillomacular bundle of fibers and results in reduced visual acuity, central scotoma, and loss of the ability to see green. Symptoms of . . . [Full Text of this Article]

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