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Figure 1. A plain abdominal film (Panel A) revealed diffuse renal calcification in a 22-year-old woman with end-stage renal disease. After two months of regular hemodialysis, skin bullae and livedo reticularis appeared on her legs, and loss of central vision and peripheral neuropathy developed. Funduscopy showed crystal deposition in the macula (Panel B). Examination of a skin-biopsy specimen revealed deposition of crystalline material in the vessel walls (arrows in Panel C) that was birefringent on polarizing microscopy (Panel D) (Panels C and D: hematoxylin and eosin, x250). Blood oxalate and glycolate concentrations were high, confirming the diagnosis of . . . [Full Text of this Article] |
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