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Previous Volume 341:2011-2013 December 23, 1999 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Plasma lipoproteins transport fats (cholesterol and triglyceride) and hence have a key role in atherosclerotic cardiovascular disease. Low-density lipoprotein (LDL) cholesterol promotes atherogenesis, and high-density lipoprotein (HDL) cholesterol inhibits it. The total and relative amounts of saturated and unsaturated fats in the diet can influence plasma lipoprotein levels and thus the risk of cardiovascular disease. This influence is due, at least in part, to the effects of dietary fats on lipoprotein receptors on the surfaces of cells that bind circulating lipoproteins tightly and mediate the internalization of lipoprotein cholesterol by cells. The discovery of LDL receptors 25 years ago by . . . [Full Text of this Article]

References

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