Edited by Reginald R. Hall. 384 pp., illustrated. London, Arnold, 1999. (Distributed by Oxford University Press, New York.) $95. ISBN 0-340-74092-2.
A little over 100 years ago, Rehn made the seminal observationthat there was a high incidence of bladder cancer among workersexposed to aniline dyes. The subsequent identification of thecarcinogens used in the manufacture of these dyes led to thefirst successful control of cancer by epidemiologic means. Inthe United States, in 1998 there were 54,000 cases of cancerof the bladder and 12,500 deaths from this disease. The widediscrepancy between incidence and mortality is accounted forby the prevalence of superficial tumors. Such tumors frequentlyrecur, but only 20 percent progress and invade the bladder . . . [Full Text of this Article]
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