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Previous Volume 341:277-278 July 22, 1999 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Over the past 100 years, the development and widespread use of vaccines against infectious agents has been one of the triumphs of medical science. One reason for the success of these vaccines is that they excel at inducing antibodies, which are the principal agents of immune protection against most viruses and bacteria. There are, however, exceptions, including medically important intracellular organisms like Mycobacterium tuberculosis, the malarial parasite, Leishmania major, and possibly the human immunodeficiency virus (HIV), in which protection depends more on cell-mediated immunity than on the induction of antibodies (humoral immunity).

All currently licensed vaccines, whether they are prepared . . . [Full Text of this Article]

References

Related Letters:

DNA Vaccines
Freis P. C., Seder R. A., Gurunathan S.
Extract | Full Text  
N Engl J Med 1999; 341:1623-1624, Nov 18, 1999. Correspondence

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